| MirGeneDB ID | Esc-Mir-2-o45 |
|---|---|
| Family name | MIR-2 (all species) |
| Species | Hawaiian bobtail squid (Euprymna scolopes) |
| MiRBase ID | |
| Paralogues | Esc-Mir-2-o47a-v1 Esc-Mir-2-o47b Esc-Mir-2-o47c Esc-Mir-2-o47d Esc-Mir-2-o48-v1 Esc-Mir-2-o49 Esc-Mir-2-P12 |
| Orthologues | Gsp-Mir-2 Npo-Mir-2-o45 Obi-Mir-2-o45-v1 Ovu-Mir-2-o45-v1 Ple-Mir-2 |
| Node of Origin (locus) | Cephalopoda |
| Node of Origin (family) | Protostomia |
| Genome context (esc-GCA_024364805.1_ASM2436480v1) |
CM044488.1: 27565591-27565650 [-] Ensembl |
| Clustered miRNAs (< 50kb from Mir-2-o45-v1) |
Mir-2-o49
CM044488.1: 27562752-27562815 [-]
Ensembl
Mir-2-o48-v1 CM044488.1: 27562855-27562918 [-] Ensembl Mir-2-o48-v2 CM044488.1: 27562855-27562918 [-] Ensembl Mir-2-o47d CM044488.1: 27563803-27563860 [-] Ensembl Mir-2-o47c CM044488.1: 27564000-27564059 [-] Ensembl Mir-2-o47b CM044488.1: 27564469-27564528 [-] Ensembl Mir-2-o47a-v1 CM044488.1: 27564797-27564854 [-] Ensembl Mir-2-o47a-v2 CM044488.1: 27564797-27564854 [-] Ensembl Mir-2-P12 CM044488.1: 27565399-27565460 [-] Ensembl Mir-2-o45-v1 CM044488.1: 27565591-27565650 [-] Ensembl Mir-2-o45-v2 CM044488.1: 27565591-27565650 [-] Ensembl Mir-71 CM044488.1: 27565864-27565922 [-] Ensembl |
| Variant | Esc-Mir-2-o45-v1 |
| Seed | CACAGCC |
| Precursor (pre-Mir +30nt flank) |
AAAAACCUGUAUGAGGAGCAGGUUGCGAAGGCAUCAAUGCUGGAUGUCAUAGUAAUCUCCUUGGCCUAUCACAGCCAGCUUUGAUGAGCCUCGUCUCCUGCCAAGCAUCACUGACUUUUUGet precursor sequence |
| Structure | 10 20 30 40 50 AAAAACCUGUAUGAGGA-- UU A --| U A C GUAAUCU GCAGG GCG AGGC AUCAA GCUGG UGU AUA \ CGUCC UGC UCCG UAGUU CGACC ACA UAU C UUUUUCAGUCACUACGAAC UC - AG^ U G C CCGGUUC . 110 100 90 80 70 60 |
| Deep sequencing | |
| Comment | It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis. |
| 3' NTU | No |
| Motifs | CNNC at 3p(+17) |
| Star sequence | Esc-Mir-2-o45-v1_5p* (predicted) |
| mirBase accession | None |
| Sequence |
0- GCAUCAAUGCUGGAUGUCAUA -21
Get sequence
|
| Mature sequence | Esc-Mir-2-o45-v1_3p |
| mirBase accession | None |
| Sequence |
38- UCACAGCCAGCUUUGAUGAGCC -60
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|
| Variant | Esc-Mir-2-o45-v2 |
| Seed | AUCACAG |
| Precursor (pre-Mir +30nt flank) |
AAAAACCUGUAUGAGGAGCAGGUUGCGAAGGCAUCAAUGCUGGAUGUCAUAGUAAUCUCCUUGGCCUAUCACAGCCAGCUUUGAUGAGCCUCGUCUCCUGCCAAGCAUCACUGACUUUUUGet precursor sequence |
| Structure | 10 20 30 40 50 AAAAACCUGUAUGAGGA-- UU A --| U A C UAAUCU GCAGG GCG AGGC AUCAA GCUGG UGU AUAG \ CGUCC UGC UCCG UAGUU CGACC ACA UAUC C UUUUUCAGUCACUACGAAC UC - AG^ U G C CGGUUC . 110 100 90 80 70 60 |
| Deep sequencing | |
| Comment | It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis. |
| 3' NTU | No |
| Motifs | CNNC at 3p(+17) |
| Star sequence | Esc-Mir-2-o45-v2_5p* (predicted) |
| mirBase accession | None |
| Sequence |
0- GCAUCAAUGCUGGAUGUCAUAGU -23
Get sequence
|
| Mature sequence | Esc-Mir-2-o45-v2_3p |
| mirBase accession | None |
| Sequence |
36- UAUCACAGCCAGCUUUGAUGAGCC -60
Get sequence
|
