MirGeneDB 3.0
MirGeneDB ID

Hsa-Mir-421-P1

Family name MIR-421 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-mir-545
Paralogues Hsa-Mir-421-P1-v1  Hsa-Mir-421-P2 
Orthologues Bta-Mir-421-P1-v1  Cfa-Mir-421-P1-v1  Cpo-Mir-421-P1  Dno-Mir-421-P1-v1  Eca-Mir-421-P1-v1  Mml-Mir-421-P1-v1  Mmr-Mir-421-P1a  Mmr-Mir-421-P1b  Ocu-Mir-421-P1-v1  Pab-Mir-421-P1 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(hg38)		 chrX: 74287126-74287185 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P1-v2)		 Mir-421-P1-v1 chrX: 74287125-74287187 [-] UCSC Ensembl
Mir-421-P1-v2 chrX: 74287126-74287185 [-] UCSC Ensembl
Mir-374-P1 chrX: 74287295-74287346 [-] UCSC Ensembl
Variant

Hsa-Mir-421-P1-v2
Seed CAGUAAA
Precursor
(pre-Mir +30nt flank)		 
CCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUAGAUGAAUAAAUGAAUGACUCAUCAGCAAACAUUUAUUGUGUGCCUGCUAAAGUGAGCUCCACAGGCUCUGGAU
Get precursor sequence
Structure
        10           20        30         40        50         
CCAGAGCCCAGCCUGGC---  A         CU-|           A  A     AUAAAU 
                    AC UUAGUAGGC   CAGUAAAUGUUU UU GAUGA      \
                    UG AAUCGUCCG   GUUAUUUACAAA GA CUACU      G
UAGGUCUCGGACACCUCGAG  A         UGU^           C  -     CAGUAA 
.       110       100        90        80         70        60
Deep sequencing
Go to detailed chart
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-421-P1-v2_5p
mirBase accessionMIMAT0004785
Sequence 
0- UCAGUAAAUGUUUAUUAGAUGA -22
Get sequence
Proposed targets microrna.org: MIMAT0004785
TargetScanVert: hsa-miR-545-5p
TargetMiner: hsa-miR-545-5p
miRDB: MIMAT0004785
Star sequence

Hsa-Mir-421-P1-v2_3p*
mirBase accessionMIMAT0003165
Sequence 
37- AUCAGCAAACAUUUAUUGUGUGC -60
Get sequence
Proposed targets microrna.org: MIMAT0003165
TargetScanVert: hsa-miR-545-3p
TargetMiner: hsa-miR-545-3p
miRDB: MIMAT0003165
Variant

Hsa-Mir-421-P1-v1
Seed CUCAGUA
Precursor
(pre-Mir +30nt flank)		 
CUCCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUAGAUGAAUAAAUGAAUGACUCAUCAGCAAACAUUUAUUGUGUGCCUGCUAAAGUGAGCUCCACAGGCUCUGGAUU
Get precursor sequence
Structure
        10          20        30         40        50        60 
CUCCAGAGCCCAGCCUGG--   A         CU-|           A  A    AAUAAAU 
                    CAC UUAGUAGGC   CAGUAAAUGUUU UU GAUG       \
                    GUG AAUCGUCCG   GUUAUUUACAAA GA CUAC       G
UUAGGUCUCGGACACCUCGA   A         UGU^           C  -    UCAGUAA 
 120       110       100        90        80         70
Deep sequencing
Go to detailed chart
3' NTU No
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-421-P1-v1_5p
mirBase accessionMIMAT0004785
Sequence 
0- CCUCAGUAAAUGUUUAUUAGAUG -23
Get sequence
Proposed targets microrna.org: MIMAT0004785
TargetScanVert: hsa-miR-545-5p
TargetMiner: hsa-miR-545-5p
miRDB: MIMAT0004785
Star sequence

Hsa-Mir-421-P1-v1_3p*
mirBase accessionMIMAT0003165
Sequence 
40- UCAGCAAACAUUUAUUGUGUGCC -63
Get sequence
Proposed targets microrna.org: MIMAT0003165
TargetScanVert: hsa-miR-545-3p
TargetMiner: hsa-miR-545-3p
miRDB: MIMAT0003165