MirGeneDB 3.0
MirGeneDB ID

Sma-Mir-2-o130

Family name MIR-2 (all species)
Species Blood fluke (Schistosoma mansoni)
MiRBase ID sma-mir-2a
Paralogues Sma-Mir-2-o131  Sma-Mir-2-o132  Sma-Mir-2-o133  Sma-Mir-2-o134  Sma-Mir-2-o135 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mansoni
Node of Origin (family) Protostomia
Genome context
(GCA_000237925.5_SM_V9_genomic)		 OU426849.1: 4544063-4544117 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o130)		 Mir-71-o5 OU426849.1: 4543971-4544024 [+] UCSC Ensembl
Mir-2-o130 OU426849.1: 4544063-4544117 [+] UCSC Ensembl
Mir-2-o131 OU426849.1: 4544155-4544212 [+] UCSC Ensembl
Mir-2-o132 OU426849.1: 4544251-4544316 [+] UCSC Ensembl
Seed CACAGCC
Precursor
(pre-Mir +30nt flank)		 
CACGAGUCGUCUGCAAUACCUCUUGCGCCGCAGUCAAUAUUGGCUGAAGGCAUUGCUUUAUUGUCACAGCCAGUAUUGAUGAACGGUGUAAAAGGCGCACGUCCACCACUGCAGG
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Structure
        10          20        30         40        50       
CACGAGUCGUCUGCAAUA--   C        CA-|             AA    UUGC 
                    CCU UUGCGCCG   GUCAAUAUUGGCUG  GGCA    \
                    GGA AAUGUGGC   UAGUUAUGACCGAC  CUGU    U
GGACGUCACCACCUGCACGC   A        AAG^             A-    UAUU 
   110       100        90        80        70         60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ad Ce Ce Ce Eg Eg Eg Eg Eg Eg Mi Mi Sc Sc Sc Sm Sm Sp Sp Sp
Star sequence

Sma-Mir-2-o130_5p*
mirBase accessionMIMAT0025029
Sequence 
0- CAGUCAAUAUUGGCUGAAGGCA -22
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Mature sequence

Sma-Mir-2-o130_3p
mirBase accessionMIMAT0025030
Sequence 
33- UCACAGCCAGUAUUGAUGAACG -55
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