Mir-221-P1a

MirGeneDB ID

Cmi-Mir-221-P1a

Family name

MIR-221 (all species)

Species

Australian ghostshark (Callorhinchus milii)

MiRBase ID

Paralogues

Cmi-Mir-221-P1c Cmi-Mir-221-P2a

Orthologues

Aca-Mir-221-P1a Ami-Mir-221-P1a Bta-Mir-221-P1a Cfa-Mir-221-P1a Cja-Mir-221-P1a1 Cja-Mir-221-P1a2 Cli-Mir-221-P1a Cpi-Mir-221-P1a Cpo-Mir-221-P1a Dno-Mir-221-P1a Dre-Mir-221-P1a1 Eca-Mir-221-P1a Ete-Mir-221-P1a Gga-Mir-221-P1a Gja-Mir-221-P1a Gmo-Mir-221-P1a1 Gmo-Mir-221-P1a2 Hsa-Mir-221-P1a Laf-Mir-221-P1a Lch-Mir-221-P1a Loc-Mir-221-P1a Mal-Mir-221-P1a1 Mal-Mir-221-P1a2 Mdo-Mir-221-P1a Mml-Mir-221-P1a Mmr-Mir-221-P1a Mmu-Mir-221-P1a Mun-Mir-221-P1a Neu-Mir-221-P1a Oan-Mir-221-P1a Ocu-Mir-221-P1a Pab-Mir-221-P1a Pbv-Mir-221-P1a Rno-Mir-221-P1a Sha-Mir-221-P1a Spt-Mir-221-P1a Sto-Mir-221-P1a Tgu-Mir-221-P1a Tni-Mir-221-P1a1 Xla-Mir-221-P1a3 Xla-Mir-221-P1a4 Xtr-Mir-221-P1a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(GCA_000165045.2_Callorhinchus_milii-6.1.3)

KI635858.1: 3691581-3691641 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-221-P1a)

Mir-221-P2a KI635858.1: 3689867-3689927 [-] UCSC Ensembl
Mir-221-P1a KI635858.1: 3691581-3691641 [-] UCSC Ensembl

Seed

GCUCAGU

Precursor
(pre-Mir +30nt flank)

GAAAAGCCUUACUCCUUGAUGUCCAUCAAUUGCUCAGUAGUCAGUGUAGAUCCUGUCUCCAUUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGCCAUCACGCUUCCUCUUGAUUUUCA

Get precursor sequence

Structure

        10           20        30        40         50         
GAAAAGCCUUACUCCUU---|   UC     AUU             -     AUCCUGUCU 
                    GAUG  CAUCA   GCUCAGUAGUCAG UGUAG         C
                    CUAC  GUAGU   UGGGUCAUCGGUC ACAUC         C
ACUUUUAGUUCUCCUUCGCA^   C-     CUC             U     GACGACUUA 
 .       110       100         90        80        70        60

Deep sequencing

Go to detailed chart

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17), UGUG in loop

Tissue expression

Bl	Br	Ey	Gi	He	In	Ki	Li	Mu	Ov	Pa	Re	Sk	Sp	Te	Ut

Mature sequence

Cmi-Mir-221-P1a_5p

mirBase accession

None

Sequence

0- UGCUCAGUAGUCAGUGUAGAUCC -23

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Co-mature sequence

Cmi-Mir-221-P1a_3p

mirBase accession

None

Sequence

37- AGCUACAUCUGGCUACUGGGUCUC -61

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