Mir-15-P1d

MirGeneDB ID

Hsa-Mir-15-P1d

Family name

MIR-15 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-497

Paralogues

Hsa-Mir-15-P1a Hsa-Mir-15-P1b Hsa-Mir-15-P1c Hsa-Mir-15-P2a Hsa-Mir-15-P2b Hsa-Mir-15-P2c Hsa-Mir-15-P2d

Orthologues

Ami-Mir-15-P1d Bta-Mir-15-P1d Cfa-Mir-15-P1d Cin-Mir-15-P1 Cja-Mir-15-P1d Cpo-Mir-15-P1d Dno-Mir-15-P1d Dre-Mir-15-P1d Eca-Mir-15-P1d Ete-Mir-15-P1d Laf-Mir-15-P1d Loc-Mir-15-P1d Mdo-Mir-15-P1d Mml-Mir-15-P1d Mmr-Mir-15-P1d Mmu-Mir-15-P1d Neu-Mir-15-P1d Oan-Mir-15-P1d Ocu-Mir-15-P1d Pab-Mir-15-P1d Rno-Mir-15-P1d Sha-Mir-15-P1d Sto-Mir-15-P1d

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Olfactores

Genome context
(hg38)

chr17: 7017938-7017999 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-15-P1d)

Mir-15-P2d chr17: 7017627-7017687 [-] UCSC Ensembl
Mir-15-P1d chr17: 7017938-7017999 [-] UCSC Ensembl

Seed

AGCAGCA

Precursor
(pre-Mir +30nt flank)

UUUCAACCCACCCCGGUCCUGCUCCCGCCCCAGCAGCACACUGUGGUUUGUACGGCACUGUGGCCACGUCCAAACCACACUGUGGUGUUAGAGCGAGGGUGGGGGAGGCACCGCCGAGGCUU

Get precursor sequence

Structure

        10          20        30        40        50        60
UUUCAACCCACCCCGGU--| UG   C   CCC    G    C         UACGGCACU 
                   CC  CUC CGC   AGCA CACA UGUGGUUUG         G
                   GG  GGG GCG   UUGU GUGU ACACCAAAC         U
UUCGGAGCCGCCACGGAGG^ GU   A   AGA    G    C         CUGCACCGG 
120       110       100        90        80        70

Deep sequencing

Go to detailed chart

Comment

There are Dicer cuts +1 and +2 on the 3p arm.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-15-P1d_5p

mirBase accession

MIMAT0002820

Sequence

0- CAGCAGCACACUGUGGUUUGUA -22

Get sequence

Proposed targets

microrna.org: MIMAT0002820
TargetScanVert: hsa-miR-497-5p
TargetMiner: hsa-miR-497-5p
miRDB: MIMAT0002820

Star sequence

Hsa-Mir-15-P1d_3p*

mirBase accession

MIMAT0004768

Sequence

40- CAAACCACACUGUGGUGUUAGA -62

Get sequence

Proposed targets

microrna.org: MIMAT0004768
TargetScanVert: hsa-miR-497-3p
TargetMiner: hsa-miR-497-3p
miRDB: MIMAT0004768